News & Topics
TEAM LEADER: Makiko YAMADA
Interdisciplinary research about human cognitive functions and neural mechanisms to understand the abnormal subjective experiences associated with psychiatric symptoms.
TEAM LEADER: Makoto HIGUCHI
Translational research bidirectionally linking animal models and humans to elucidate molecular etiology of neuropsychiatric disorders.
ASSISTANT DIRECTOR: Naruhiko SAHARA
Aims of our research are to develop animal models for neurodegenerative and neuropsychiatric diseases
TEAM LEADER: Takafumi MINAMIMOTO
Basic research on the neural and molecular mechanism of motivation, emotion and memory using non-human primates.
Outline of Research
Schizophrenia is a mental disorder, with the main symptoms involving delusion, hallucination, inferential thinking and negative symptoms.
Mood Disorder is a mental disorder that has disturbance in mood or emotion as a main symptom, and it causes depressive episodes. Bipolar Disorder is characterized by the repetition of depressive and manic episodes.
Alzheimer's disease is characterized by the dementia and pathology defined by the presence of hallmark lesions in the brain. The disease may have large impacts on the societies with growing elderly population.
Most drugs used for mentalDisorders function by bindingto receptors of neurotransmit-ters in brain and blocking orreinforcing their signal tranmission.
Among neural networks,dopamine neural activation in the cerebral cortex is especially considered to play an important role in cognition, reward and memory.
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